This ipamorelin dosage chart keeps two things apart that most dosing pages blend together: the doses published studies actually gave, and the amounts people on Reddit say they inject. The published doses are intravenous and weight-based. The Reddit amounts are flat subcutaneous numbers. Neither is a prescription, because ipamorelin has no approved dose in any country we could verify.
Key Takeaways
- The only human dosing data are intravenous: five levels from about 3 to 100 mcg/kg in healthy men (1999), and 0.03 mg/kg twice daily in a 2014 bowel-surgery trial. No study tested the 100 to 300 mcg subcutaneous routine people follow
- Among 24 Reddit accounts that gave a clear per-injection amount, 100 mcg (7) and 200 mcg (6) were the most common. This is a small, self-selected sample, not a recommendation
- Water volume decides the unit count: a 5 mg vial with 2 mL is 2,500 mcg/mL, so 200 mcg is 0.08 mL, or 8 units on a U-100 syringe
- Common online ceilings such as "300 mcg per shot" are community convention. We found no human study that shows GH response stops rising there
- Ipamorelin is a research peptide, not an FDA-approved drug, and growth hormone secretagogues are banned in tested sport. This page is information, not medical advice
For what the compound is and how the evidence stacks up overall, see our ipamorelin peptide guide. This page is the dose-focused companion, and our ipamorelin benefits page covers what the evidence says about the outcomes.
Ipamorelin dosage chart: what the published studies used
Start with the table, because it answers the question most people arrive with: what number appears in a paper. The honest answer is that every human number is intravenous, and none matches what is sold in a 5 mg vial.
Ipamorelin doses as written in published studies
| Dose as published | Route and schedule | What it was | |
|---|---|---|---|
| Rat and swine potency, 1998 | ED50 for GH release: 80 nmol/kg in rats (about 57 mcg/kg), 2.3 nmol/kg in swine (about 1.6 mcg/kg) | Single dose, anaesthetised rats and conscious swine | Animal, selectivity work; no cortisol or ACTH rise even at over 200 times the ED50 |
| Healthy men, 1999 | 5 levels: 4.21 to 140.45 nmol/kg (about 3 to 100 mcg/kg) | Intravenous, over 15 minutes, one dose per level | Human, 8 men per level; half-life 2 hours; GH released at every level |
| Postoperative ileus, 2014 | 0.03 mg/kg (30 mcg/kg) | Intravenous, twice daily, up to 7 days | Human, 114 analysed; meal tolerance 25.3 h vs 32.6 h on placebo, p = 0.15 |
| Rat bone work, 1999 to 2001 | 18, 90 or 450 mcg/day; 0.5 mg/kg/day; 100 mcg/kg three times daily | Subcutaneous or minipump, 15 days to 3 months | Animal, bone length and mineral content |
| Approved label | None | None | Ipamorelin has no FDA-approved use or label dose |
The human pharmacology comes from a 1999 dose-escalation study in healthy men. Eight men at each of five infusion levels received ipamorelin over 15 minutes. Converting the published nmol/kg figures gives about 3, 10, 30, 60 and 100 mcg/kg. The authors reported dose-proportional kinetics, a terminal half-life of about 2 hours, and a single pulse of growth hormone that peaked at roughly 40 minutes at every dose (PMID 10496658). For an 80 kg adult, the lowest level works out to roughly 240 mcg given intravenously, and the highest to about 8 mg.
The second human source is a 2014 phase 2 trial in 114 analysed patients recovering from bowel resection, who received 0.03 mg/kg intravenously twice daily for up to seven days (PMID 25331030). That is about 2.4 mg per infusion in an 80 kg person. The drug was well tolerated, but median time to a first tolerated solid meal was 25.3 hours on ipamorelin and 32.6 on placebo (p = 0.15), so it did not show a benefit for the gut problem it was tested on. Adverse events occurred in 87.5 percent of the ipamorelin group and 94.8 percent of placebo.
The animal work explains where the "selective" label came from. In swine, ipamorelin released growth hormone without raising ACTH or cortisol, even at doses more than 200 times the dose needed for the growth hormone effect, which GHRP-6 and GHRP-2 did not manage (PMID 9849822). The later rat studies dosed from 18 mcg a day to 0.5 mg/kg a day for up to three months and looked at bone, not at anything a person would feel (PMIDs 10373343, 10828840, 11735244).
Why published doses do not convert into a subcutaneous dose
Anyone can do the arithmetic: 200 mcg in an 80 kg person is 2.5 mcg/kg, a bit below the lowest intravenous level in the 1999 study. That tells you the community amount is not absurdly high compared with the research, and it tells you almost nothing else. Intravenous and subcutaneous routes differ in how fast and how fully a peptide reaches the blood, and the 1999 paper does not give a subcutaneous equivalent.
It also undercuts a claim you will see repeated. Many guides, including our own existing overview, describe the response flattening around 300 to 400 mcg. The human abstract we could verify says ipamorelin released growth hormone at all five dose levels and reports no plateau, and the trial only went up to about 100 mcg/kg. We did not find a source for the 300 mcg ceiling, so treat it as convention. One Reddit commenter went further and claimed that 200 mcg "had no effect" in the early human work. The abstract does not say that either; it says growth hormone was released at every level.
Two practical consequences follow. First, the flat 100 to 300 mcg figures on vendor pages are not derived from a trial. Second, anything you read about "diminishing returns" is a statement about what people prefer, not about a measured saturation point.
What Reddit users report taking
To see what people do in practice, we read 302 posts and comments from 25 threads across ten subreddits, returned by searches on ipamorelin and CJC-1295 dosage, mostly from 2025 to October 2026. After removing bot and moderator notices, jokes, vendor mentions, deleted comments and questions that gave no number, 35 comments from 9 threads and 5 subreddits (mainly r/BodyHackGuide) described what the writer took or was prescribed. Of those, 24 gave a clear per-injection ipamorelin amount, 11 gave only a combined or unclear amount, and 22 of the 24 were in a range of 100 to 400 mcg.
What 24 Reddit accounts say they inject per dose of ipamorelin
The mode was 100 mcg, usually taken once at night, and 200 mcg was next. Most people were using a CJC-1295 (no DAC) and ipamorelin blend, so the numbers often refer to each peptide in a combined vial. Of the 20 accounts that stated a frequency, 13 dosed once a day, 6 split the dose between morning and evening, and 1 injected every other day. Thirteen of all 35 mentioned five days on and two days off. Planned lengths were 8 weeks (1 account), 10 weeks (1), 12 weeks (3) and "8 to 12 weeks" (1), with one person running 3 to 6 month cycles with 1 to 2 months off. Nobody cited evidence for any of it.
Titration was common. One commenter, dosing 100 mcg of each, wrote: "There will eventually be a point of diminishing returns, so ideally the lowest dose with a noticeably benefit is ideal." (a r/PeptidePathways commenter, May 2026, link). Sleep was the commonest complaint: six commenters described disrupted sleep, a racing heart or being wide awake at night after raising a dose or at a particular injection time. Some fixed it by dropping the dose or moving to mornings, while one found a morning dose left them awake at 2 am. A r/BodyHackGuide commenter (Mar 2026) put it as "Pay attention to your sleep. If you are waking up then lower the dosage." (link).
Two outliers need flagging. A r/CJC1295_IPAMORELIN user described a prescription as 2,000 mcg, 0.5 mL twice a day, and a r/CJC1295_IPAMORELIN commenter (May 2025) replied "Hopefully you mistyped it! 2000mcg is extremely high!" (link). That user also reported feeling sick after two weeks and a new autoimmune diagnosis, which we cannot link to the drug either way. Separately, one commenter in a different thread said they take 1 mg a night. A single person tolerating a dose is not a safety study, and a typo in mg versus mcg is the most plausible explanation for some of these numbers.
The sample has limits worth stating. Nearly all the accounts come from communities that exist to discuss these products, nobody can verify vial contents, and many were asking for help rather than reporting. Counts here are reproducible from the data file, but they describe who posted, not what works.
Reconstitution math: mcg, mL and syringe units
Most Reddit dosing threads turn out to be reconstitution threads. The vial holds a fixed mass of powder, and the water you add only sets the concentration, so the same dose takes more or less volume. The formula is units on a U-100 syringe = dose in mcg divided by concentration in mcg/mL, times 100.
A worked example: a 5 mg vial reconstituted with 2 mL of bacteriostatic water is 5,000 mcg in 2 mL, or 2,500 mcg/mL. A 200 mcg dose is 200 divided by 2,500, which is 0.08 mL, or 8 units on a syringe where 100 units equals 1 mL.
Syringe units for common ipamorelin doses (U-100 syringe)
| Concentration | 100 mcg | 200 mcg | 300 mcg | |
|---|---|---|---|---|
| 5 mg + 1 mL | 5,000 mcg/mL | 2 units | 4 units | 6 units |
| 5 mg + 2 mL | 2,500 mcg/mL | 4 units | 8 units | 12 units |
| 5 mg + 3 mL | 1,667 mcg/mL | 6 units | 12 units | 18 units |
| 10 mg + 3 mL | 3,333 mcg/mL | 3 units | 6 units | 9 units |
Scaling by vial size is just division. A 5 mg vial holds 50 doses of 100 mcg, 25 of 200 mcg or about 16 of 300 mcg. A 10 mg vial holds twice as many. At 200 mcg a day, five days a week, a 5 mg vial lasts five weeks; at 200 mcg twice daily it lasts about two and a half. A 12-week course at 200 mcg five days a week uses 60 doses, or 12 mg, which is more than two 5 mg vials.
Blends add a trap. In a 5 mg plus 5 mg vial with 3 mL of water, each peptide is about 1,667 mcg/mL, so 12 units delivers 200 mcg of each. Two commenters in the data undercounted: one said 8 units gave 125 mcg of each and another that 10 units gave 125 mcg, when the same arithmetic gives about 133 and 167. People also asked whether "200 mcg" of a blend means 200 total or 200 of each. Write the units out, name the peptide, and recompute whenever you change the water volume.
The vial is the other half of the math. If a product contains less peptide than its label says, every number above is off. Our guide on where to buy ipamorelin explains how to read a certificate of analysis. If you want one supplier to check against, Ascension Peptides sells a 5 mg ipamorelin vial at $50.00 as of 2026-10-11 ($10.00 per mg). Kovera Labs tests every batch (HPLC, LC-MS identity, net content, endotoxin, sterility and heavy metals), more than 98 percent of tested batches pass, and batch certificates are public. Prices are in US dollars, shipping is US only and all sales are final. New customers can use code PEPTIDEDECK for 50 percent off. It is sold as a research chemical, not for human use.
Timing, frequency and cycle length
The short half-life, about two hours in the human study, is the reason people split doses or inject nightly. Each dose produces one pulse that is gone within hours, so more injections means more pulses, not a bigger one. No study compared schedules in people.
On timing, the Reddit accounts split between bedtime and morning. Both groups mentioned injecting at least two to three hours after eating, because food and the insulin it triggers are said to blunt the response. That is a mechanism argument rather than something these commenters measured. One commenter avoided morning doses because of daytime water retention; others switched to mornings because night doses kept them awake.
Cycle length is the weakest area. The human trials ran one dose or seven days. Reddit mentions cluster at 8 to 12 weeks, and the reasons given for breaks are convention. If you read a source claiming ipamorelin never desensitises the receptor, note that we found no long-term human data either way.
What changes the dose
These variables are said to matter, though none can be quantified.
Route. The human studies were intravenous. Subcutaneous self-injection is a different experiment, and we found no human dose data for any other route.
Body weight. The research doses are per kilogram; community charts are flat. Whether a 55 kg and a 110 kg person should inject the same amount is untested.
A GHRH partner. Most Reddit users combined ipamorelin with CJC-1295 (no DAC), and several said that was why they used small doses. See our comparison of CJC-1295 vs ipamorelin for how the two work together.
Meal timing and sleep. Dose and injection time interact. A dose that was fine in the morning cost some commenters their sleep at night.
Health conditions and other drugs. Growth hormone raises insulin resistance and fluid retention. Anyone with diabetes, a cancer history or on prescription drugs should talk to a clinician first. Our ipamorelin side effects page covers the documented and reported adverse effects.
Product quality. An underfilled vial makes two people on the "same dose" report different results.
Frequently Asked Questions
What is the ipamorelin dosage?
There is no established dosage. The human studies used intravenous doses of about 3 to 100 mcg/kg in healthy men and 0.03 mg/kg twice daily in surgical patients. The Reddit accounts we counted most often named 100 mcg or 200 mcg per injection, mostly with CJC-1295.
How many units is 200 mcg of ipamorelin?
It depends on the water you added. With a 5 mg vial and 2 mL, the concentration is 2,500 mcg/mL, so 200 mcg is 8 units on a U-100 syringe. With 1 mL it is 4 units, and with 3 mL it is 12 units.
How much ipamorelin per day do people take?
Of 20 Reddit accounts with a stated frequency, 13 injected once a day, 6 twice a day and 1 every other day. Daily totals ranged from 100 mcg to 800 mcg, with a few unverified outliers far higher. These are anecdotes, not guidance.
How long should you run ipamorelin?
No study defines a cycle length. Reddit mentions cluster at 8 to 12 weeks, sometimes with 1 to 2 months off, and none of them cites evidence.
Is ipamorelin FDA-approved?
No. It has not been approved by the FDA for any use and is sold as a research chemical. Its compounding status has changed in recent years and we could not verify the current position, so ask a clinician or pharmacist instead of assuming.
Checking a vial before you do any math
The dose arithmetic assumes the label is true, so confirm lot, purity and mass first. Ascension Peptides lists the 5 mg vial at $50.00 as of 2026-10-11, with per-batch Kovera Labs testing and public batch certificates; US shipping only and all sales are final. Write units out in full, and treat every Reddit number here as an anecdote.
Medical Disclaimer: Ipamorelin is an investigational research peptide. It is not approved by the FDA or any comparable regulator for any condition and is sold for laboratory research use only. This article reports published and user-reported figures for education. It is not medical advice, a dosing protocol or a recommendation for personal use. Consult a qualified healthcare professional about any health concern.
